Shipping Systems
Temperature-Controlled Shipping Systems
Purpose-built solutions for every temperature band, supported by uncompromising quality and process control.
Cryoport Systems offers the industry’s most advanced temperature-controlled shipping solutions, designed specifically for the unique requirements of the life sciences. Whether you’re moving cellular starting material, high-value biologics, or finished therapies, our integrated systems protect your commodities across the full temperature spectrum from cryogenic (-150°C and below), to ultra cold (-60°C to -80°C), refrigerated (2°C to 8°C), and controlled room temperature (15°C to 25°C).
Each system is backed by purpose-built packaging, continuous condition monitoring, and global logistics support, all connected through the Cryoportal® Logistics Management Platform and supported by 24/7/365 oversight. With our combination of proprietary technology, rigorous processes, and deep expertise, Cryoport Systems enables the safe, compliant, and efficient transport of critical materials at every phase of development.
From our Veri-Clean® process to robust requalification of shipping systems before every use, Cryoport Systems sets the standard for quality and safety in the temperature-controlled supply chain.
Precision Control Across the Full Thermal Spectrum
Select the range that matches your product’s stability needs.
Every therapy has a temperature sweet spot. Cryoport Systems delivers validated solutions for all the most critical temperature bands, so you never have to compromise on safety, efficacy, or compliance.
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Cryogenic (≤ -150 °C)
Our industry-leading LN₂ dry-vapor shippers safeguard the most sensitive cellular and genetic materials at temperatures at or below -150°C with robust quality and compliance.
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Ultra Cold (-60 to -80°C)
Validated systems preserve vaccines, gene therapies, viral vectors, and specialty biologics in the ultra-cold range while providing near real-time data and audit-ready reports.
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Refrigerated & CRT (2-8°C / 15-25°C)
The C3™ Solution maintains stable refrigerated or controlled-room-temperature conditions, ideal for biologics, diagnostics, and finished pharmaceuticals.
Unmatched Quality, Traceability, and Performance
Veri-Clean® and Requalification
Purpose-built for science, Veri-Clean® is the industry’s only validated cleaning and disinfection process for cryogenic shippers.
Our proprietary Veri-Clean® process removes cross-contamination risk with validated cleaning protocols that exceed industry standards. Each shipper is also fully tested, validated, and requalified before every use, ensuring performance integrity and compliance across shipments.
Chain of Compliance®
From origin to destination, we don’t just track location… we track the condition, handling, and history of every asset.
Our proprietary Chain of Compliance® is the industry’s most robust process that ensures traceability and accountability across your cold chain. We document equipment usage, maintenance, cleaning, and calibration to create an unbroken chain of control for every shipment. This is especially critical for audits, regulatory filings, and process validation.
Advanced Therapy Shippers (ATS)
Designed specifically for cell and gene therapies, our ATS shipping systems protect what matters most: your patients and your science.
We maintain a fully-segregated fleet of cryogenic, ultra cold, refrigerated, and controlled room temperature shipping systems specifically for advanced therapies. This enables full ISO 21973 compliance by ensuring complete segregation of shipping systems that transport human cells for therapeutic use, adding another layer of protection and risk mitigation to your end-to-end supply chain management.
ISO 21973 Compliance
We don’t just meet ISO 21973, we helped shape how it’s implemented across the industry.
Cryoport Systems was instrumental in shaping ISO 21973, the international standard for the transportation of cell and gene therapies. Our adherence to these guidelines reflects our commitment to traceability, risk mitigation, and patient safety at every step.
Cryoportal® & Continuous Monitoring
Full, continuous visibility and control integrated into every shipment.
Our Cryoportal® Logistics Management Platform connects data from Smartpak™ sensors with route planning, documentation, and risk management tools. Clients benefit from automated alerts, complete shipment histories, and centralized access to logistics data. It’s the backbone of our end-to-end visibility promise.
Track Record of Success
Proven in the most demanding environments with the most sensitive materials.
Cryoport Systems supports over 700 clinical trials and multiple commercial therapies worldwide. Our systems have been trusted by leading pharmaceutical, biotech, and cell therapy companies to protect some of the world’s most complex and valuable therapies, from R&D to global commercialization. With more than 950,000 successful shipments and in support of 20 commercialized therapies, you can count on our track record of success to deliver the industry’s most compliant, risk mitigating solutions.
Six Shipping Systems, One Standard of Excellence
Choose the right system for your payload size, route, and risk profile.
From small clinical shipments to pallet-scale transfers, each of our shipping systems is engineered for performance, traceability, and re-use, and backed by our Veri-Clean® decontamination and requalification process and industry-leading compliance and quality standards.
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Cryoport Express® Standard
Lightweight LN₂ dry-vapor shipper offering up to 10 days of cryogenic hold time with Smartpak™ monitoring.
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Cryoport Express® Combo
Dual-purpose cryogenic unit with an enlarged accessory tray, ideal for mixed ambient + frozen payloads.
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Cryoport Express® HV3
High-volume cryogenic solution optimized for larger sample sets and extended routes.
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Cryomax® Palletized Shipper
Industry-leading capacity (28 k+ vials) and 21-day hold time ideal for lab moves.
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Cryoport Elite® Ultra Cold
Reusable ultra-cold shipper that keeps materials at -60 °C to -80 °C with integrated Smartpak™ visibility.
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C3™ Shipping System
Versatile 2-8 °C or 15-25°C platform combining phase-change packaging with Smartpak II® for near real-time control.
Unrivaled protection for the most advanced therapies.
Cryoport Systems delivers purpose-built shipping solutions across every temperature band, backed by technology, traceability, and a proven track record, empowering you to move science forward with confidence.